Garcinia Cambogia Appears to be Very Safe Bottle With Blue Pills It is important to keep in mind that these studies usually only report averages. It is possible that some individuals can in fact lose weight with this supplement, although it doesnt seem to work very well on average. At least, Garcinia Cambogia appears to be safe. There are no serious side effects, only some reports of mild digestive issues (14). It is best to get a brand with at least 50 Hydroxycitric acid.